Studies of the medicinal plant Pausinystalia yohimbe ethanol leaf extract phytocomponents by GCMS analysis

Abstract

An in vitro phytochemical study of ethanolic leaf extract of Pausinystalia yohimbe was done using Gas Chromatography-Mass Spectrometry to identify the presence or absence of erectile compounds. The chromatogram of the leaf of Pausinystalia yohimbe showed eight peaks indicating the presence of eight phytocompounds. The most abundant compound was Linoleic acid with a [Retention Time: 22.689; Peak Area: 52.99% ; Molecular Formula: C₁₈H₃₂O₂] followed by n-Hexadecanoic acid with [Retention Time:19.91; Peak Area: 15.87% ; Molecular Formula: C₁₆H₃₂O₂] followed by 2-Methylene-11-hexadecanoic acid with [Retention Time: 21.774; Peak Area: 7.57% ; Molecular Formula of C₁₇H₂₈O₂]. Other components identified were 2,4-Dimethy-1,3-dioxane, n-Hexadecanoic acid, methyl ester, 11-phenyundecanoic acid, Octadecanoic acid and 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one. The bioactivities of Pausinystalia yohimbe leaf extract were anti-carcinogenic, lipid metabolism regulation, antioxidation, anti-atherosclerotic and antifungal from the GCMS result. Therefore the leaf of Pausinystalia yohimbe may be having bioactivities different from the bark which is known to contain yohimbine for erectile disfunction.

Keywords

• GCMS
• Pausinystalia yohimbe
• Linoleic acid
• n-Hexadecanoic acid
• 2
• 4- Dimethyl-1
• 3- dioxane